منابع مشابه
Emerging trends in the discovery of natural product antibacterials.
This article highlights current trends and advances in exploiting natural sources for the deployment of novel and potent anti-infective countermeasures. The key challenge is to therapeutically target bacterial pathogens that exhibit a variety of puzzling and evolutionarily complex resistance mechanisms. Special emphasis is given to the strengths, weaknesses, and opportunities in the natural pro...
متن کاملNatural Product Research: Formerly Natural Product Letters
New sesquiterpenoid derivatives from Solanum septemlobum with cytotoxicities Lei Zhang, Hai-Qing Lin, Gui-Sheng Li, Xi-Dian Yue & ShengJun Dai a School of Pharmaceutical Science, Yantai University, Yantai 264005, P.R. China b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical Coll...
متن کاملNatural Product Research: Formerly Natural Product Letters
Anthemis wiedemanniana essential oil prevents LPS-induced production of NO in RAW 264.7 macrophages and exerts antiproliferative and antibacterial activities in vitro Filomena Conforti a , Federica Menichini a , Carmen Formisano b , Daniela Rigano b , Felice Senatore b , Maurizio Bruno c , Sergio Rosselli c & Sezgin Çelik d a Department of Pharmaceutical Sciences , University of Calabria , via ...
متن کاملNatural product and natural product derived drugs in clinical trials.
There are a significant number of natural product (NP) drugs in development. We review the 100 NP and NP-derived compounds and 33 Antibody Drug Conjugates (ADCs) with a NP-derived cytotoxic component being evaluated in clinical trials or in registration at the end of 2013. 38 of these compounds and 33 ADCs are being investigated as potential oncology treatments, 26 as anti-infectives, 19 for th...
متن کاملFucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells.
BACKGROUND Although the antitumor effects of fucoxanthin are known, the precise mechanism of action has yet to be elucidated. MATERIALS AND METHODS HepG2 and DU145 cells were used for these investigations. The effect of fucoxanthin on gene expression was assayed using a DNA microarray system. Northern blot and/or quantitative RT-PCR were carried out to confirm any changes in gene expression. ...
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ژورنال
عنوان ژورنال: Ege Journal of Fisheries and Aquatic Sciences
سال: 2021
ISSN: 2148-3140,1300-1590
DOI: 10.12714/egejfas.38.1.15